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Brought to you by Diabetes & Primary Care, the three mini-case studies presented here take you through the considerations of managing complex cases of hypertension in type 2 diabetes. This module should be worked through once you have completed Managing hypertension in diabetes – the basics. Each scenario provides a different set of circumstances that you could meet in your everyday practice. By actively engaging with them, you will feel more confident and empowered to manage effectively such problems in the future


  1. NICE (2019) Hypertension in adults: diagnosis and management (NG136).
  2. Williams B, MacDonald TM, Morant S et al; British Hypertension Society’s PATHWAY Studies Group (2015) Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised double-blind, crossover trial. Lancet 386: 2059–68
  3. de Boer IH, Bangalore S, Benetos A et al (2017) Diabetes and Hypertension: A position statement by the American Diabetes Association. Diabetes Care 40: 1273–84
  4. Fleg JL, Evans GW, Margolis KL et al (2016) Orthostatic hypotension in the ACCORD blood pressure trial: prevalence, incidence and prognostic significance. Hypertension 68: 888–95
  5. Arguedas JA, Leiva V, Wright JM (2013) Blood pressure targets for hypertension in people with diabetes mellitus. Cochrane Database Syst Rev 10: CD008277
  6. Zhao P, Xu P, Wan C, Wang Z (2011) Evening versus morning dosing regimen drug therapy for hypertension. Cochrane Database Syst Rev 10: CD004184
  7. Hermida RC, Ayala DE, Mojón A, Fernández JR (2011) Influence of time of day of blood pressure-lowering treatment on cardiovascular risk in hypertensive patients with type 2 diabetes. Diabetes Care 34: 1270–6

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