Cardiovascular disease - DiabetesontheNet

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Cardiovascular disease

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Diabetes Distilled: Dapagliflozin and heart failure outcomes in people with and without type 2 diabetes

Results of the DAPA-HF trial of dapagliflozin in people with heart failure with reduced ejection fraction, with or without pre-existing type 2 diabetes.

4 May 2020

Polypharmacy increases mortality and MI in elderly with diabetes

16 Jan 2020

Diabetes Distilled: 2019 ADA/EASD consensus update proposes expanded role for GLP-1 RAs in atherosclerotic CVD

What's new in the 2019 update to the ADA/EASD type 2 diabetes consensus guidance?

13 Jan 2020

15th National Conference of the PCDS: Part 1

The key learning points and their application to practice from the broad range of topics presented at the conference.

20 Dec 2019

Editorial: The 2019 ESC/EASD guidelines: Comprehensive and controversial

The broad-ranging recommendations from the ESC and ADA, and the implications for primary care.

20 Dec 2019

At a glance factsheet: How to read a cardiovascular outcome trial (CVOT)

Guidance on how to read and understand the findings of these important clinical studies.

19 Dec 2019

GLP-1 receptor agonists significantly improve CV outcomes

12 Dec 2019

GLP-1 receptor agonists have a wide range of benefits

12 Dec 2019

Early blood pressure control reduces atherosclerotic event risk

12 Dec 2019

Early intensive multifactorial therapy reduces stroke risk

12 Dec 2019

Canagliflozin effective in primary and secondary prevention of CV outcomes

12 Dec 2019

Diabetes Distilled: Controversial metformin recommendations in new ESC guidance

European guidance reflects new evidence on risk management in diabetes and pre-diabetes.

21 Nov 2019

Diabetes Distilled: Blood pressure variability linked to cardiovascular outcomes in diabetes

Increased risk of major cardiovascular events predicted by long-term systolic blood pressure variability.

21 Nov 2019

Blood pressure variability linked to CV outcomes in diabetes

Blood pressure variability (BPV) is considered a novel risk factor for cardiovascular disease, as clinical trials have confirmed that short- and long-term variations in blood pressure independently contribute to target organ damage, cardiovascular events and mortality. In this systematic review and meta-analysis, investigators examined the relationship between BPV and all-cause mortality, major adverse cardiovascular events, microvascular complications and organ damage in type 2 diabetes. They found that in adults with type 2 diabetes, systolic BPV was associated with adverse outcomes and concluded that variation in blood pressure provided information beyond mean blood pressure on the risk of cardiovascular disease in these individuals.

12 Nov 2019

Controversial metformin recommendations in new ESC guidance

The latest European Society of Cardiology guidelines on diabetes, pre-diabetes and cardiovascular diseases recognise that considerable emerging evidence should have implications for daily clinical practice. Controversially, metformin is no longer recommended as first-line treatment in type 2 diabetes. Suggestions for the prevention of cardiovascular disease, advice on lifestyle intervention, new lipid and blood pressure targets, a novel approach to glucose-lowering treatment, diabetes treatment aimed at reducing heart failure risk, and cardiovascular risk management are included. The guidance has been developed in collaboration with the European Association for the Study of Diabetes and updates recommendations made in 2013.

12 Nov 2019

At a glance factsheet: Diagnosis and management of hypertension in adults: Updated NICE guidance 2019

The key changes to NICE guidance on hypertension in adults.

23 Oct 2019

Diabetes Distilled: Practitioner empathy impacts long-term diabetes outcomes

Lower risk of cardiovascular events and mortality following positive early experiences of practitioner empathy.

16 Oct 2019

NICE hypertension guidance: What’s new?

An in-depth review of the new NICE NG136 guideline on hypertension and the changes that have been made from previous guidance.

10 Oct 2019

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