Your web browser is out of date.

For your security and improved experience online, please update your browser.

This site is intended for healthcare professionals only
×
News
Share this article
Share on facebook
Share on twitter
Share on email
Share on print

Landmark trial shows type 2 diabetes remission with intensive low-calorie diet

Journal of Diabetes Nursing – Winter newsletter

Landmark trial shows type 2 diabetes remission with intensive low-calorie diet.

Nearly half (45.6%) of those who took part in a primary-care based weight management programme were in remission from type 2 diabetes after 12 months.
 
DiRECT (Diabetes Remission Clinical Trial) is a 2-year trial assessing the effectiveness of a structured weight management programme delivered through primary care across Scotland and Tyneside. Lead researchers, Professor Mike Lean from the University of Glasgow and Professor Roy Taylor from Newcastle University, presented the first year results at the International Diabetes Federation Congress in Abu Dhabi last week.
 
Fror the purposes of the study, remission was defined as having HbA1c of less than 48 mmol/mol (6.5%), with at least two months without any type 2 diabetes medications.
 
Of the 298 people with type 2 diabetes participating in the study, half received standard diabetes care from their GP, while the other half received a structured weight management programme within primary care. The programme included a low calorie for 3–5 months, food reintroduction and long-term support to maintain weight loss.
 
The link between weight loss and remission was clear. Almost 9 out of 10 people (86%) who lost 15kg or more put their type 2 diabetes into remission, as well as 57% of those who lost 10 to 15kg. Only 4% of the control group achieved remission.
 
Professor Mike Lean said: “Putting Type 2 diabetes into remission as early as possible after diagnosis could have extraordinary benefits, both for the individual and the NHS. DiRECT is telling us it could be possible for as many as half of patients to achieve this in routine primary care, and without drugs.”
 
The trial findings have been published in the Lancet: https://doi.org/10.1016/S0140-6736(17)33102-1

Share this article
Share on facebook
Share on twitter
Share on linkedin
Share on email
Share on whatsapp
For the latest news and articles

Sign up to all DiabetesontheNet journals

© Copyright Omniamed Communications. All Rights Reserved​
108 Cannon Street, London, EC4N 6EU. Registered in the United Kingdom​
Omniamed logo white
For the latest news and articles

Sign up to all DiabetesontheNet journals

 

By clicking ‘Subscribe’, you are agreeing that DiabetesontheNet.com are able to email you periodic newsletters. You may unsubscribe from these at any time. Your info is safe with us and we will never sell or trade your details. For information please review our Privacy Policy.

DiabetesontheNet Logo

This website is for UK healthcare professionals only. To continue, please confirm that you are a UK healthcare professional below.