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Diabetes &
Primary Care
Issue:
Vol:23 | No:05
Diabetes Distilled: Clarity and consensus on diabetes remission
Previous definitions of remission differed in different countries, causing confusion about remission diagnosis and ongoing surveillance. An expert panel, representing the Endocrine Society, the European Association for the Study of Diabetes, Diabetes UK and the American Diabetes Association (ADA), has published a consensus report on the definition and interpretation of remission in type 2 diabetes.
Consensus was reached on the following areas:
The authors identified areas requiring further exploration: Should a different HbA1c value or CGM measure be used to define remission, or CGM measures? What is the optimal timing of repeat testing? Are there benefits in continuing metformin? What happens to gut hormones? Is there variation in the duration of remission depending on how it is achieved? And what are the long-term outcomes, including complications, quality of life and function?
Consensus authors’ notes
A consensus report contains a comprehensive examination of a topic by an expert panel and usually includes analysis, evaluation and opinion. A consensus report is needed when clinicians, scientists, regulators and/or policy makers seek guidance and/or clarity on a medical or scientific issue for which the evidence is contradictory, emerging or incomplete. The expert panel can also identify gaps in evidence and propose areas of future research.
This consensus report, published simultaneously in The Journal of Clinical Endocrinology & Metabolism, Diabetologia, Diabetic Medicine and Diabetes Care, reflects the joint working of the expert representatives of the organisations in preparation of the consensus. The authors highlight that it should not be seen as an ADA Position Statement or as a treatment guideline, but rather it proposes definitions and ways to assess glycaemia, and facilitate collection and analysis of data.
To read the report in full, click here.
Riddle MC, Cefalu WT, Evans PH et al (2021) Consensus report: Definition and interpretation of remission in type 2 diabetes. Diabet Med 30 Aug [Epub ahead of print]
Rolling out tirzepatide for weight management: NHS England recommendations
Diabetes Distilled: Heart and SOUL – oral semaglutide demonstrates cardiovascular benefit in high-risk people with type 2 diabetes
NICE overweight and obesity guidelines – what’s new?
PCDO Society National Conference 2025: Request for poster abstracts
Diabetes Distilled: Time to intensify blood pressure treatment in people with type 2 diabetes?
How to undertake a multiple long-term conditions review
Diabetes Distilled: Preserving muscle is important when using incretin mimetics for weight loss
Satish Durgam reviews who will be eligible to receive tirzpepatide for weight management and when.
24 Apr 2025
Results of SOUL trial suggest oral semaglutide offers similar cardiovascular benefits to the injectable formulation.
22 Apr 2025
The new NG246 guideline replaces several pre-existing NICE obesity guidelines. Sally Erskine reviews the key changes.
15 Apr 2025
Poster abstract submissions are invited for the 21st National Conference of the PCDO Society, which will be held on 19 and 20 November.
10 Apr 2025