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Insulin pump treatment (INPUT) education programme improves glycaemic control in CSII patients

Devices – January 2019 digest

Review of the INPUT randomised-controlled study in people using continuous subcutaneous insulin infusion.

Ehrmann D, Kulzer B, Schipfer M et al (2018) Efficacy of an education program for people with diabetes and insulin pump treatment (INPUT): results from a randomized controlled trial. Diabetes Care 41: 2453–62

  • Continuous subcutaneous insulin infusion (CSII) use leads to significant reductions in HbA1c levels compared to multiple daily injections and avoids the use of injections but costs considerably more and its effects on hypoglycaemia have been inconclusive.
  • Structured education is needed to provide users with the knowledge and skills to successfully use CSII and keep them motivated. A specific CSII education Insulin Pump Therapy (INPUT) programme incorporating clinical, technological and psychosocial aspects of self-management was developed and its effect on glycaemic control compared to standard care studied in a randomised controlled trial.
  • Researchers randomly allocated 268 CSII therapy users (mean duration of CSII use = 9.5 years) to the INPUT group or control group and measured participants’ HbA1c at baseline and 6 months and the incidence of hypoglycaemia during that period.
  • The average HbA1c of the INPUT group had improved from 8.33% to 8.04% at 6 months (P<0.0001) whereas there was little change in the control group, which was 8.33% at the start of the study and 8.27% after 6 months (P=0.11). There was a significant between-group difference in favour of the INPUT group (P=0.0029).
  • The incidence of severe hypoglycaemia was 3.55 times higher in the control group than the INPUT group.
  • Participation in the INPUT education programme resulted in a significant reduction in HbA1c level and the incidence of hypoglycaemia in patients using CSII.

Click here to access the study in full.

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