Investigators were aware that visual acuity loss is a common consequence of type 2 diabetes and may complicate diabetes self-management. They investigated patients with newly-diagnosed type 2 diabetes to assess whether loss of visual acuity was an independent risk factor for mortality in this population. They found that impaired visual acuity at diagnosis was associated with increased all-cause mortality, independent of other risk factors for mortality.
Investigators wanted to examine whether variation in HbA1c, the degree of variability and how HbA1c varies over time predict hospitalisation and mortality in individuals with type 2 diabetes. They performed a retrospective analysis of a large cohort of patients from UK primary care and found that HbA1c variability was strongly associated with overall mortality and emergency hospitalisation. This was not explained by average HbA1c or hypoglycaemic episodes. Findings were similar for emergency hospitalisations; however, increasing average HbA1c rather than variability was predictive of emergency hospitalisation for coronary artery disease and ischaemic stroke. Investigators suggest that clinical targets should focus on both the stability and absolute level of HbA1c.
Neonatal death, stillbirth, congenital anomaly, large and small for dates babies and neonatal unit admission in diabetic pregnancies remain very high when compared to non-diabetic pregnancies. According to the latest National Pregnancy in Diabetes Audit, women with diabetes are not adequately prepared for pregnancy, with almost 90% not receiving risk-reducing pregnancy preparation as recommended by the National Institute for Health and Care Excellence. These findings have remained unchanged over the past 5 years.
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