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SMBG in non-insulin treated type 2 diabetes: New meta-analysis on clinical effects

A meta-analysis of individual patient data published in the BMJ this week has concluded that data regarding the effect of self-monitoring of blood glucose (SMBG) in non-insulin treated type 2 diabetes were “not convincing for a clinically meaningful effect”, compared with no SMBG.

Data from 2552 patients randomised in the six included trials were analysed, and the authors identified a mean reduction in HbA1c level of −2.7 mmol/mol (–0.25%; 95% confidence interval −3.9 to −1.6) for those using SMBG, compared levels compared with those not using SMBG at 6 months. The investigators did not observe any between-group differences in systolic blood pressure (−0.2 mm Hg, 95% confidence interval −1.4 to 1.0), diastolic blood pressure (−0.1 mm Hg, −0.9 to 0.6), or total cholesterol level (−0.1 mol/L, 95% confidence interval −0.2 to 0.1).

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