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Determinants of concordance with diabetes medications

People with diabetes often take a large variety of medications. A recent study has identified factors that are associated with people who have type 2 diabetes not taking their medications as prescribed. The study suggests that non-compliance is relatively common, particularly in people newly diagnosed with the condition. People between 25 and 44 years of age were 49% less likely to adhere to prescribed therapy than patients between 45 and 64 years old.

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by Colin Kenny, GP, Dromore

 

This retrospective analysis of a large American pharmacy database examined more than 200,000 patients for medication history and prescriber factors linked to concordance with antidiabetes drugs. The researchers found that older men who had a higher educational level and a higher income, and who attended primary care and, surprisingly, had a higher pill burden, were more likely to adhere to diabetes regimens. People who were new to diabetes therapy were significantly less likely to have good concordance.

The researchers concluded that it is important to think about demographic and clinical factors that impact on concordance with antidiabetes medications. In particular, they suggested that it is important to consider that people with type 2 diabetes typically perceived to be more healthy (those who are younger, more recently diagnosed with diabetes, and taking few other medications) might be at risk for non-concordance.

 

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