Your web browser is out of date.

For your security and improved experience online, please update your browser.

This site is intended for healthcare professionals only
×
News
Share this article
Share on facebook
Facebook
Share on twitter
Twitter
Share on linkedin
LinkedIn
Share on email
Email
Share on print
Print

Dapagliflozin: An effective adjunctive treatment in type 1 diabetes

Many people with type 1 diabetes continue to have high HbA1c levels despite insulin therapy, with an associated elevated risk of cardiovascular events and increased mortality. Adjunctive prescription of a sodium–glucose cotransporter 2 (SGLT2) inhibitor in type 1 diabetes has been approved as a potential intervention. In this case series, the authors report the outcomes of six adults with type 1 diabetes who initiated on dapagliflozin in East Cheshire. Over a 6-month period, mean HbA1c fell from 78.5 mmol/mol (9.3%) to 55 mmol/mol (7.2%). Analysis of flash glucose monitoring data showed that the proportion of readings in the target range (4–10 mmol/L) increased from 33.1% to 65.2% following addition of dapagliflozin, while the proportion of readings above target (>10 mmol/L) decreased from 68.0% to 26.4%. Dapagliflozin was well tolerated and improved glycaemic control with no increase in hypoglycaemia rates.

Click here to access

Share this article
Share on facebook
Share on twitter
Share on linkedin
Share on email
Share on whatsapp
For the latest news and articles

Sign up to all DiabetesontheNet journals

© Copyright Omniamed Communications. All Rights Reserved​
108 Cannon Street, London, EC4N 6EU. Registered in the United Kingdom​
Omniamed logo white
For the latest news and articles

Sign up to all DiabetesontheNet journals

 

By clicking ‘Subscribe’, you are agreeing that DiabetesontheNet.com are able to email you periodic newsletters. You may unsubscribe from these at any time. Your info is safe with us and we will never sell or trade your details. For information please review our Privacy Policy.

DiabetesontheNet Logo

This website is for UK healthcare professionals only. To continue, please confirm that you are a UK healthcare professional below.