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Association between smoking cessation and glycaemic control in T2D

Smoking habit in people with diabetes remains a very significant concern. We know that smoking increases the risk of developing diabetes, and this risk persists even in those who quit smoking. In a new analysis, researchers examining a very large primary care database have found that people with type 2 diabetes who quit smoking have a deterioration in glycaemic control that lasts for 3 years, irrespective of whether they gain weight or not.

by Colin Kenny, GP, Dromore


Over 10,000 adult smokers with type 2 diabetes were assessed using THIN (The Health Improvement Network), which is a large UK primary care database. Researchers applied a complex analysis to discover the association between a “quit smoking” event, smoking abstinence duration, change in HbA1c and the influence of weight change.

Of 10,692 adult smokers with type 2 diabetes, 3131 (29%) quit smoking and remained abstinent for at least 1 year. Their HbA1c increased by 0.21% within the first year after quitting. HbA1c decreased as abstinence continued and became comparable to that of continual smokers after 3 years. This increase in HbA1c was not mediated by weight change.

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